Covalent Modification of DNA Regulates Memory Formation
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چکیده
منابع مشابه
Covalent Modification of DNA Regulates Memory Formation
DNA methylation is a covalent chemical modification of DNA catalyzed by DNA methyltransferases (DNMTs). DNA methylation is associated with transcriptional silencing and has been studied extensively as a lifelong molecular information storage mechanism put in place during development. Here we report that DNMT gene expression is upregulated in the adult rat hippocampus following contextual fear c...
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ژورنال
عنوان ژورنال: Neuron
سال: 2007
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2007.02.022